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Ddb1- and cul4-associated factor 13

WebClinVar archives and aggregates information about relationships among variation and human health. WebDDB1 and CUL4 associated factor 17. Normal Function. The DCAF17 gene provides instructions for making a protein whose function is unknown. The gene is active (expressed) in several organs and tissues in the body, including the brain, skin, and liver. Within cells, the protein produced from this gene is found in the nucleolus, which is a small ...

DCAF13 is essential for the pathogenesis of preeclampsia through …

WebOct 1, 2024 · Male infertility is a common condition affecting at least 7% of men worldwide and is often genetic in origin. Using whole exome sequencing, we recently discovered … WebDDB1 is also a component of an ubiquitin-E3 ligase complex and functions as substrate or adapter protein between Cullin 4A (Cul4A) and CUL4-associated factors (DCAFs) to target substrates for ubiquitination. CUL4-DDB1 E3-ligase complex regulates the selective proteolysis of key proteins in DNA repair, replication and transcription. hopital saint palais numero https://dreamsvacationtours.net

Expression profiling of WD40 family genes including DDB1- and …

WebMar 29, 2024 · HIV-1 Vpr co-localizes with the Cul4A ubiquitin ligase complex (Cul4A, DCAF1, and DDB1) in the cellular chromatin compartment. PubMed. vpr. HIV-1 Vpr induces the degradation of APOBEC3G through VprBP binding and participation of the proteasome, leading to a reduction in APOBEC3G encapsidation into virions. PubMed. WebDCAF13P3 (DDB1 And CUL4 Associated Factor 13 Pseudogene 3) is a Pseudogene. Additional gene information for DCAF13P3 Gene HGNC (43868) NCBI Entrez Gene … WebUsing whole exome sequencing, we recently discovered three hemizygous, likely damaging variants in DDB1- and CUL4-associated factor 12-like protein 1 (DCAF12L1) in men with azoospermia. DCAF12L1 is located on the X-chromosome and as identified by single cell sequencing studies, its expression is enriched in human testes and specifically in ... hopital saint paul hanoi

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Ddb1- and cul4-associated factor 13

DCAF16 Gene - GeneCards DCA16 Protein DCA16 Antibody

WebDDB1 and CUL4 associated factor 13 (DCAF13) is a protein coding gene located on chromosome 8q22.3, which is a hotspot amplified in various cancers. DCAF13 has been … WebDec 4, 2024 · DDB1- and CUL4-associated factor 13, WD repeat and SOF domain-containing protein 1, WD repeats and SOF1 domain containing GeneRIFs: Gene …

Ddb1- and cul4-associated factor 13

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WebThe cullin 4 (CUL4)-damage-specific DNA binding protein 1 (DDB1)-cereblon (CRBN) E3 ubiquitin ligase co-exists in the same complex with and promotes the degradation of ClC …

WebJul 1, 2007 · DCAF13 (DDB1 and CUL4 associated factor 13) is a potential oncogene but little is understood about the developmental roles of this highly conserved gene. We characterized the RNAi phenotypes of ... WebMar 1, 2009 · Transcriptional activation of p16 is associated with H3K4 trimethylation. A, ... CUL4-DDB1 and MLL1 are required for oncogene-induced p16 ... Ohtani et al previously …

WebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) enhances the survival and maintenance of multipotent cells through promoting the Cullin 4 E3 ligase complex … WebThe cullin 4 (CUL4)-damage-specific DNA binding protein 1 (DDB1)-cereblon (CRBN) E3 ubiquitin ligase co-exists in the same complex with and promotes the degradation of ClC-2 channels. The CRBN-targeting immunomodulatory drug lenalidomide and the cullin E3 ligase inhibitor MLN4924 promotes and attenuates, respectively, proteasomal …

WebOct 11, 2004 · Protein DDB1- and CUL4-associated factor 15 Gene DCAF15 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 600 …

WebWant to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun content. Link to this page: hôpital saint omer helfautWebNov 13, 2007 · DDB1- and CUL4-associated factor 13 Gene DCAF13 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 445 Protein … hopital saint pole melunhttp://www.hitpredict.org/htp_int.php?Value=49777 hopital saint sebastien rixheimWebJul 1, 2007 · DCAF13 (DDB1 and CUL4 associated factor 13) is a potential oncogene but little is understood about the developmental roles of this highly conserved gene. hopital saint sebastienWebDDB1- AND CUL4-ASSOCIATED FACTOR 13; DCAF13 Alternative titles; symbols WD REPEAT- AND SOF1 DOMAIN-CONTAINING PROTEIN 1; WDSOF1 HGNC Approved … hopital saint pierre kineWebJun 13, 2008 · The human DDB1-CUL4 ASSOCIATED FACTOR (DCAF) proteins have been reported to interact directly with UV-DAMAGED DNA BINDING PROTEIN1 (DDB1) through the WDxR motif in their WD40 domain and function as substrate-recognition receptors for CULLIN4-based E3 ubiquitin ligases. ... we found that full-length DCAF1 … hôpital saint pierre palavasWebAlso found in: Dictionary, Medical . Acronym. Definition. DDAVP. Desmopressin Acetate (synthetic analogue of the pituitary hormone 8-arginine vasopressin) DDAVP. 1-Desamino-8d-Arginine Vasopressin. DDAVP. Deamino-Delta-D-Arginine Vasopressin (hematology) hopital saint pierre ophtalmologie